Leica S (Typ 006) vs Leica Q2

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Larger sensor
Medium format vs 35mm
More sensor area. Bigger is (generally) better.
Bigger pixels
~ 6.00 vs 4.30 microns
Better low-light and dynamic range (all else equal)
Top deck display
Yes vs No
Check settings with a screen on top of the camera
HDMI out
HDMI out vs None
Use HDMI output to monitor or review video
More viewfinder magnification
1.09x vs 0.76x
Get a bigger view of the scene through the eye-level viewfinder
Dual card slots
Yes vs No
Gives you more storage flexibility

Focus peaking
Peaker vs Non-peaker
Your camera will highlight what's in focus
In-Camera Image Stabilization
Yes vs No
Reduces the effects of camera shake at slower shutter speeds
Shoot 4K video
4K (DCI) vs No
Make sure you have a fast computer
Touchscreen
Touch vs No touch
Interact with your camera just like your smartphone
In-camera panoramas
Yes vs No
Stitches multiple shots into a panoramic photo
Built-in Wi-Fi
Wi-Fi vs None
Share your photos wirelessly
Built-in Bluetooth
Yes vs No
Always-on wireless connectivity
Higher max flash sync
1/500 vs 1/125 sec
Reduce the effect of ambient light in flash shots
Newer
5 years vs 11 years old
Newer cameras often support more advanced features
Shoots 24p video
Yes vs No
Gives your movies a big-screen feel
Lighter weight
718g vs 1260g
Lighter weight
Shoots 1080p video
Yes vs No
You'll want this if you shoot video
More pixels
47.3 vs 37.5 megapixels
Higher resolution photos
Shoots 60p video
Yes vs No
A faster framerate can give you more editing options
Longer exposure
120 vs 32 sec
Long exposures for night shots
Faster JPEG shooting
20.0 fps vs 1.5 fps
Faster JPEG shooting (burst mode)
Slow-motion videos
Yes vs No
Shoot slow-motion videos
Faster shutter
1/40000 vs 1/4000 sec
Shoot wide open in bright light
Higher extended ISO
50000 vs 1600 ISO
Higher extended ISO can give more low-light flexibility

Rear display
Both provide
Review photos on the back of the camera
Eye-level viewfinder
Both provide
You'll be able to frame photos even when the sun is out
RAW file ability
Both provide
Gives you more flexibility to develop your photos later
Manual focus
Both provide
AF is for the weak. Real photographers focus manually.
Hot shoe
Both provide
Off-camera flashes open new possibilities
Bulb shutter
Both provide
Hold the shutter open manually for long exposures

Tilt-swivel screen
Neither provide
Tilt and swivel the screen for maximum shooting flexibility
Tiltable Screen
Neither provide
Tilt the screen for shooting flexbility
NFC
Neither provide
Simplifies pairing your camera with supported phones
Built-in GPS
Neither provide
Geotag your photos
On-sensor phase detect
Neither provide
Usually improves live view and video AF performance
Internal flash
Neither provide
Useful in a pinch for fill flash
Integrated ND filter
Neither provide
Shoot in daylight with a large aperture or slow shutter
External Mic Jack
Neither provide
Improved sound fidelity when shooting video
Headphone jack
Neither provide
Monitor audio recording while you shoot video